What is Phenylpiracetam?
Phenylpiracetam is a relatively novel nootropic drug, also known as Phenotropil and Carphedon. As the name indicates, the compound is actually a phenylated analog of piracetam. It was originally developed in Russia in 1983, and is prescribed as a drug over there. The drug was not known outside the Russian Federation till mid of 2010s, when its use lead to disqualification of Olga Pyleva and Roman Usov (Olympic athletes) after the positive dope test. The drug is banned by World Anti-Doping Agency because it improves physical strength and enhance the sports performance even in extreme weather conditions. Besides this, the drug is commonly used for cognitive enhancement, psycho stimulation and improving locomotion.
How does Phenylpiracetam work?
The addition of a phenyl group to piracetam, makes it capable of crossing the blood-brain barrier easily. As a result, even smaller doses of phenylpiracetam can be more effective than higher doses of other nootropic drugs. For example, it is about 30-60 times more potent than that its parent piracetam with same weight. The benefits associated with phenylpiracetam are similar to those of piracetam. It is expected that the users of phenylpiracetam can attain increased memory, efficient recall, improved learning capacity, better focus as well as greater mental energy. There exists preliminary studies, suggesting that the drug can be effective in cognitive decline due to dementia or stoke. It is also assumed that the drug can be helpful in overcoming stress and anxiety. In addition, the drug is popular among bodybuilders for increasing stamina and endurance .
Effects of Phenylpiracetam
As the drug was initially not known to the globe except Russia, the clinical studies are either not available, or these are in Russian language. Especially there is lack of studies for prolonged use of the drug so very little is known about dependency issues, withdrawal symptoms or about any complications for prolonged use. It is generally suggested that this supplement should be taken on need basis (take as you need, and stop when the need fulfil). As most of the data about the drug is unpublished, and some facts are claimed by the manufacturers only. For example, it is claimed that the drug has 100% bioavailability and saturation is achieved within one hour. Manufacturers also claim that phenylpiracetam is indigestible, thus it is either excreted without any change, or is absorbed integrally to the blood stream. This suggests that the compound is not a pro-drug for any other chemicals.
Recommended Dosage / Usage Instructions
Anecdotally, Phenylpiracetam is taken at a dosage of 100-200mg acutely, and this dose is taken 2-3 times per day (totaling a daily range of 200-600mg). The optimal dosage is dependent on each individual and should be slowly groped.
Side-Effects of Phenylpiracetam
It is reported that administering the drug can cause difficulty in sleeping, so it should be taken early in the day, and not in evening or late afternoon. There is very little data on side effects, but there can be adverse effects with higher doses. One should consult a specialist for recommendation of dose, according to his/her own medical conditions and projected benefits.
Phenylpiracetam is not recommended to be used by pregnant or lactating women as well as children. Patients with kidney or liver disorders should also be careful before taking Phenylpiracetam.
 - The phenotropil treatment of the consequences of brain organic lesions - http://www.ncbi.nlm.nih.gov/pubmed/16447562